NFL anytime TD best bets are a popular way for bettors to approach opening Sunday, offering bigger prices than traditional sides and totals. Below are five anytime touchdown selections for Week 1, with odds provided by FanDuel Sportsbook.
If you like longer numbers on role players, you might look to options such as Keaton Mitchell at +340 or Jeremiyah Love at +205, or even a quarterback like Kyler Murray to score at +275. Our five picks aim for a balance between value and plausibility, rather than short-priced favorites or extreme long shots.
Odds courtesy of FanDuel Sportsbook.
NFL anytime TD best bets for Week 1
With Mike Evans no longer in Tampa Bay, second-year wideout Emeka Egbuka is positioned for a prominent role with Baker Mayfield. He opened his rookie campaign with 25 receptions, 445 yards and five touchdowns across his first five games, and he draws a Cincinnati Bengals defense that still has issues to resolve.
2. Eagles RB Saquon Barkley (-115)
Saquon Barkley has scored at least one touchdown in eight straight games against Washington. Given that history, and considering Washington fielded the league’s statistically worst defense last season at 384 yards allowed per game, the price near even money stands out.
Philadelphia will unveil a revamped offense, but Barkley remains central as both runner and receiver. For those targeting first TD markets, +500 is also on the board.
3. Ravens QB Lamar Jackson (+250)
Lamar Jackson endured a hamstring-plagued 2025, finishing with career lows of 349 rushing yards and two rushing scores. Healthy again, he faces an Indianapolis Colts front that is not considered elite.
With three new starters inside along Baltimore’s offensive line, Jackson may need to create outside structure with his legs. Historically, he has excelled in openers, with Baltimore averaging 33.3 points in Week 1 starts for Jackson.
4. Chargers WR Quentin Johnston (+130)
Quentin Johnston has stacked consecutive seasons of 700 receiving yards and eight touchdowns after a slow start to his career. With Mike McDaniel now coordinating the Los Angeles Chargers offense, Johnston’s vertical speed could be featured.
His preseason 65-yard connection from Justin Herbert with the starters hints at an expanded downfield role.
5. Jaguars CB/WR Travis Hunter (+950)
The Jacksonville Jaguars host the Cleveland Browns, who traded down in the 2025 draft before Jacksonville selected Travis Hunter at No. 2 overall. While Hunter is expected to log more snaps at cornerback this year, a situational offensive package remains likely.
With the Browns visiting, coordinator Liam Coen could script a red-zone touch to showcase the two-way talent at a sizable return.
Other random player props I like
- Cam Ward to throw an INT (+102): The New York Jets were shut out in interceptions last season, but a takeaway lands here.
- Aaron Jones Over 28.5 rushing yards (-116): Even with Jordan Mason expected to lead the ground game, Jones should see enough work against his former team to clear this mark.
- Malik Willis Over 40.5 rushing yards (-110): He surpassed this number in all three of his starts with the Green Bay Packers.
- Isaiah Likely Over 35.5 receiving yards (-112): With Mark Andrews not in New York, Likely projects for a steady target share, especially with Malik Nabers not at full strength.
- Jahmyr Gibbs longest rush Over 18.5 (-112): Backed to pop at least one explosive run against the New Orleans Saints.
Bettors weighing these options can also consider how they pair with broader NFL Week 1 betting angles and game scripts. Many of the same matchups will influence touchdown props, yardage totals and interception markets.
Those placing wagers through FanDuel Sportsbook should ensure their accounts are funded and any bonus offers are activated before kickoff. For official team and player status updates, checking the latest reports from the NFL can help inform final decisions on these props.